December 12, 1843

Cover vol. 12, no. 6, December 2015

Granada , Spain December 12 th - 15 th

s 16 location of Presentations 15

Persian-translation vol. 12, no. 6, December 2015

Dmd059709 1843..1850

Although tamoxifen is a successful agent for treatment and prevention of estrogen-dependent breast cancer, its use has been limited by the low incidence of endometrial cancer. Human hydroxysteroid sulfotransferase 2A1 (hSULT2A1) catalyzes the formation of an a-sulfooxy metabolite of tamoxifen that is reactive toward DNA, and this has been implicated in its carcinogenicity. Also, hSULT2A1 functi...

Camillo Golgi (1843?1926)

Camillo Golgi studied the central nervous system [2] during the late nineteenth and early twentieth centuries in Italy, and he developed a staining technique to visualize brain cells. Called the black reaction, Golgi's staining technique enabled him to see the cellular structure of brain cells, called neurons, with much greater precision. Golgi also used the black reaction to identify structure...